منابع مشابه
ExACtly zero or once
Objective: To assist the interpretation of genomic data for common epilepsies, we asked whether variants implicated in mild epilepsies in autosomal dominant families are present in the general population. Methods: We studied 12 genes for the milder epilepsies and identified published variants with strong segregation support (de novo germline mutation or $4 affected family members). These varian...
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A three-tier application is organized as three layers. Front end clients (e.g., browsers) with which human user interact; middle-tier servers (e.g., web servers) that contain the core business logic of the application; and back-end database servers against which application servers perform transactions. Although three-tier applications are nowadays mainstream, they usually fail to provide su ci...
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Today's web-based E-services do not handle system failures well. One of the most prominent examples is unintentional purchase of multiple copies of the same item (e.g., a DVD) in an online store. This may happen when the user sees a browser timeout for the final “checkout” (“place order”) request caused by a short outage or overload of the network or the backend servers (typically during peak l...
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In recent years, stream processing has emerged as a data analysis technique to handle real-time applications where the latency of Hadoop is unacceptable. Many popular systems, such as Twitter’s Storm, provide a rigid platform for performing distributed computations over the network. Stormlike systems typically provide at-least-once processing with state management left to the implementor. We pr...
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ژورنال
عنوان ژورنال: Neurology Genetics
سال: 2017
ISSN: 2376-7839
DOI: 10.1212/nxg.0000000000000163